Do you need any help, in terms of manpower/labor with any of your manufacturing/production activities? If you can provide the necessary materials, equipment/tools and instructions we might be able to assist. We have able and capable manufacturing associates who are currently idle and looking for work to keep themselves busy. If you need support in any of the processes listed below, feel free to reach out:
• Assembly work
• Prototype
• Machining, fabrication of parts/fixtures
• Mechanical drafting – Solidworks
• Documentation – document review & gap analysis
• Testing
• Inspection
• Test method development
• Computer system validation
• System/Equipment validation

Visit us at www.Pilnm.com for more information

Researchers could rapidly obtain high-resolution images of blood vessels and neurons within the brain.

Microscopy technique makes finer images of deeper tissue, more quickly
A team of researchers has developed a modified version of two-photon imaging that can scan deeper within tissue and perform the imaging much faster than previously possible.

Source: Massachusetts Institute of Technology

To create high-resolution, 3D images of tissues such as the brain, researchers often use two-photon microscopy, which involves aiming a high-intensity laser at the specimen to induce fluorescence excitation. However, scanning deep within the brain can be difficult because light scatters off of tissues as it goes deeper, making images blurry.

Two-photon imaging is also time-consuming, as it usually requires scanning individual pixels one at a time. A team of MIT and Harvard University researchers has now developed a modified version of two-photon imaging that can image deeper within tissue and perform the imaging much more quickly than what was previously possible.

This kind of imaging could allow scientists to more rapidly obtain high-resolution images of structures such as blood vessels and individual neurons within the brain, the researchers say.

Microscopic Image

Effect of PCI devices on Automation Systems

Figure 1 shows a typical industrial Programmable Logic Controller (PLC) design where one core is dedicated to Windows* supporting an application running a legacy device (such as a PCI device) and the other core is dedicated to a RTOS that supports a real time application running on Intel® Ethernet controller I210.

Industry 4.0 is changing systems architecture across all domains in industrial automation. Upcoming edge computing architectures use virtualization for scaling dedicated applications with deterministic key performance indicators (KPIs) on a heterogeneous operating systems. This enables an industrial control application to be configured to have dedicated cores assigned to different operating systems. For example, a motion controller can have a core dedicated to real time operating system (such as VxWorks*) to execute real-time workloads and another core assigned to a general purpose operating system (such as Windows*) to run other applications that are not time-sensitive.

Legacy device application run on Windows* and often frequently initiate bulk and high-speed data transfers from the CPU to the device via the system network. Real-time application run on RTOS and also demand system network resources by generating continuous compute requests to CPU core (for example, real time application running on Intel® Ethernet Controller I210 generate interrupts to be executed via the interrupt service routine (ISR)).. As time progresses, transactions from legacy device congest the system network as PCI-express to PCI Bridge stalls the ongoing traffic because PCIe ordering rules don’t support such bulk high-frequency data transfers to a PCI device. This degrades the Quality of Service (QoS) and disturbs the time synchronization for real time application. In cloud computing, this phenomena is known as the “noisy neighbor” effect.

Vikram Dadwal

Starting a new manufacturing project can be daunting. Weighing the costs and benefits of outsourcing to a contract manufacturer can seem downright overwhelming. You may feel like you will be giving up control of your project by choosing to go with a contract manufacturing company, or, have concerns that turnaround times or scheduling will become a massive headache you don’t want to deal with. It doesn’t have to be like that.

Experienced contract manufacturers like PIL&M can make the outside contracting experience incredibly easy on your nerves and your schedule. What many people don’t realize is that contract manufacturing can be as simple as handling one small component or piece of a product, or as involved as lending the assistance of experienced, collaborative engineers to help with product designs, prototyping, and even supply chain management. A good contract manufacturer will anticipate these concerns and provide you with valuable project management resources and a dedicated contact to make the manufacturing process a smooth one.

When you choose a contract manufacturer, you also avoid other costs—like maintenance of a manufacturing facility and expensive manufacturing equipment, quality control inspection systems and much more. Visit us at www.Pilnm.com for further details.

1. Identify and Eliminate manufacturing errors at point of commission
2. Simplify information and control systems; integrate them efficiently with design and production.
3. Cooperate and Coordinate with suppliers and service providers to share knowledge and increase joint effectiveness.
4. Pull production stingily through the factory pipeline instead of mindlessly pushing material and labor into it.
5. Build and Ship rapidly to improve manufacturing productivity, rather than storing and moving inventory.
6. Squeeze Time out of the cycle from order receipt through shipment by eliminating redundant tasks and tasks that do not contribute directly to output or quality.
7. Improve product design to enhance manufacturability and provide increased functionality and reliability to the customer.
8. Reduce per-unit consumption of purchased material and supplies.
9. Refine the production process to promote simplicity and decrease resource consumption.
10.Strive continually for incremental improvements in an activities involved with design and delivery of the product to the customer.

Working with the right design team makes a huge difference regarding how quickly you gain market entry over your competition. Not long ago, a client approached us with their ideas for a renal therapy device. They provided information regarding their desired features, functionality, performance specifications, the expected time to launch, and cost per unit. With just a mere amount of information about their ideas, we were able to come up with a 3D sketch. From the 3D design model, we created their first iteration prototype in a few weeks. Following weeks of design verification testing, design alterations, changes in material selections, and repeated design verification testing, we were able to come up with the first sets of prototypes for in-vitro benchmark tests. Altogether, in a matter of less than 8 months, we were able to turn an idea from concept to full product realization. So, it does make a difference who you work with when selecting a design team. Do you have an idea that you continue to shelf because you think it will be too expensive to pursue?

At PIL&M Inc, we specialize in making your ideas become reality in a short period of time and at a cost-effective rate. For further inquiries visit us at; www.pilnm.com

Cheap laser weld, pay as low as $1 for each weld. For more about our advanced laser engineering development, visit us at: https://pilnm.com/laser-weld-laser-cutting-consulting/

There is so much value in working with our product development team. Our product development services are methodically tailored to meet your unmet needs.
Do you have an idea that you are unable to execute as a result of budget constraint, lack of resources or equipment? With your commitment, we can help explore your design concept(s) and provide your team with the required
products/components. Our approach can be a turn-key development, or we can work collaboratively with your team until the desired product/component is attained. For more information contact us today, www.Pilnm.com

Cheap laser weld for all your laser weld requirements, pay as little as almost nothing to get your parts welded.

For more about our advanced laser engineering development, visit us at: https://pilnm.com/laser-weld-laser-cutting-consulting/

Are you looking for a laser welding service company where you can build your proof of concept samples prior to investing a huge sum of money on a laser system that you may not even need? Let PIL&M, expert in laser welding and laser cutting engineering consulting services help develop your laser welding and laser cutting processes. We have over 25years of engineering consulting services and we can assist with all your laser welding and laser cutting applications. Many of our current clients are from the Biotech industry, so we are accustomed to welding and cutting small parts as small as 0.025″ OD to whatever size your parts may be. We do not charge for your first article or feasibility samples and we guarantee all our work. Your satisfaction is fully guaranteed, thus if you are not happy with our work we will redo it for you. Let PIL&M, expert in laser welding and laser cutting engineering consulting services research the most suitable option for your application and provide all the samples you need. And as you are ready to transfer into production you can use our developed processes to set up your line. We also provide technology transfer service where we will provide your team with all tribal knowledge and including process validation of your line.

For more about our advanced laser engineering development, visit us at: https://pilnm.com/laser-weld-laser-cutting-consulting/

Use this link for images of our weld samples